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Beilstein J. Org. Chem. 2018, 14, 2853–2860, doi:10.3762/bjoc.14.264
Graphical Abstract
Scheme 1: Malonate-based retrosynthesis of α-amino esters.
Scheme 2: Some side products and synthesis of α-amino ester 10.
Scheme 3: Syntheses of α-amino esters 22, 24, 26, 28 and 33.
Scheme 4: Syntheses of α-amino esters 38, 41 and 46a,b.
Scheme 5: Syntheses of α-amino esters 53 and 58.